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Can I read Histogenesis in 11-Day Mouse Embryo Limb Buds Explanted in Organ Culture on EtoBox?
Histogenesis in 11-Day Mouse Embryo Limb Buds Explanted in Organ Culture by J. Milaire; J. Mulnard is a Environmental Science article available to read on EtoBox.
What is Histogenesis in 11-Day Mouse Embryo Limb Buds Explanted in Organ Culture about?
Fore-and hindlimb buds from 11-day mouse embryos with 40 to 52 somites (including the four occipital pairs) were explanted in organ culture and submitted to systematic histological analysis. Chondrogenesis occurs normally in culture in all preskeletal rudiments which were already represented by condensed blastemas before explantation. In the proximal territories, the progress of cartilage differentiation occurs according to the normal pattern and can be revealed histologically much earlier than in bulk preparations. In all explanted hindlimbs as well as in forelimbs from embryos with less than 50 somites, a primary coalescence occurs between the IId and IIId digital rays, leading to various fusions from soft tissue syndactyly to oligosyndactyly. This is the result of two combined unfavorable effects of the culture conditions: the lack of simultaneous volumetric growth of the footor handplate, which normally would provide the necessary space for the laying down of a pentadactylous pattern, and a loss of cells resulting from abnormal cell death affecting selective mesodermal sites in the zeugopod and in the marginal subridge area, the latter being more severely affected in hindlimb b
Who reads Histogenesis in 11-Day Mouse Embryo Limb Buds Explanted in Organ Culture?
It is typically read by researchers, students, and practitioners in Environmental Science.
- Author
- J. Milaire; J. Mulnard
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0022-104X)
- Published
- 1984
- Language
- EN
- Field
- Environmental Science (Life Sciences)