Can I read Childhood Adversity and Pain Facilitation on EtoBox?

Childhood Adversity and Pain Facilitation by You, Dokyoung S.; Meagher, Mary W. is a Medicine article available to read on EtoBox.

What is Childhood Adversity and Pain Facilitation about?

## ABSTRACT ## Objective This study investigated whether childhood adversity would be associated with hypersensitivity on two measures of central pain facilitation: area of secondary allodynia and temporal summation of second pain (TSSP), and whether pain facilitation would be explained by adult posttraumatic stress disorder (PTSD) symptoms. ## Method Participants endorsing high (__n__ = 31) and low (__n__ = 31) childhood adversity underwent capsaicin-induced secondary allodynia and TSSP testing. The tests were conducted a week apart with test order counterbalanced. ## Results Larger areas of secondary allodynia were observed in the high adversity group compared with the low adversity group (__F__(1,60) = 4.81, __p__ = .032). This group difference was largely (62%) explained by greater PTSD symptoms in the high adversity group. Although no overall difference was found in TSSP slopes (__p__ = .886), this was attributed to an order by group interaction (__F__(1,58) = 5.07, __p__ = .028) and low power. Subsequent analyses revealed positive TSSP slopes in the high adversity group when TSSP testing was performed first, and this order effect was associated with blunted sympathetic respon

Who reads Childhood Adversity and Pain Facilitation?

Author

You, Dokyoung S.; Meagher, Mary W.

Publisher

Lippincott Williams and Wilkins; Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins; Lippincott Williams & Wilkins Ltd.; Ovid Technologies (Wolters Kluwer Health) (ISSN 0033-3174)

Published

2018

Language

EN

Field

Medicine (Health Sciences)