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Review: Long non-coding RNA in livestock by B. Kosinska-Selbi; M. Mielczarek; J. Szyda is a Agricultural and Biological Sciences article available to read on EtoBox.

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Less than 2% of mammalian genomes code for proteins, but 'the majority of its bases can be found in primary transcripts' - a phenomenon termed the pervasive transcription, which was first reported in 2007. Even though most of the transcripts do not code for proteins, they play a variety of biological functions, with regulation of gene expression appearing as the most common one. Those transcripts are divided into two groups based on their length: small non-coding RNAs, which are maximally 200 bp long, and long non-coding RNAs (lncRNAs), which are longer than 200 nucleotides. The advances in next-generation sequencing methods provided a new possibility of investigating the full set of RNA molecules in the cell. In this review, we summarized the current state of knowledge on lncRNAs in three major livestock species - Sus scrofa, Bos taurus and Gallus gallus, based on the literature and the content of biological databases. In the NONCODE database, the largest number of identified lncRNA transcripts is available for pigs, but cattle have the largest number of lncRNA genes. Poultry is represented by less than a half of records. Genomic annotation of lncRNAs showed that the majority of t

Who reads Review: Long non-coding RNA in livestock?

Author

B. Kosinska-Selbi; M. Mielczarek; J. Szyda

Publisher

Cambridge University Press; Cambridge University Press (CUP); Research Square; Elsevier BV (ISSN 1751-7311)

Published

2020

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)