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Can I read Sequence complexity and DNA curvature on EtoBox?
Sequence complexity and DNA curvature by Andrei Gabrielian; Alexander Bolshoy is a Chemistry article available to read on EtoBox.
What is Sequence complexity and DNA curvature about?
A linguistic complexity measure was applied to the complete genomes of HIV-1, Escherichia coli, Bacillus subtilis, Haemophilus in ̄uenzae, Mycoplasma genitalium, and to long human and yeast genomic fragments. Complexity values averaged over entire genomic sequences were compared, as were predicted average values of intrinsic DNA curvature. We found that both the most curved and the least complex fragments are located preferentially in noncoding parts of the genome. Analysis of location of the most curved and the simplest regions in bacteria showed that the low-complexity segments are preferentially located in close proximity to the highly curved sequences, which are, in turn, placed from 100 to 200 bases upstream to the start of the nearest coding sequence. We conclude that the parallel analysis of sequence complexity and DNA curvature might provide important information about sequence±structure±function relationship in genomes.
Who reads Sequence complexity and DNA curvature?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Andrei Gabrielian; Alexander Bolshoy
- Publisher
- Elsevier Science; Elsevier ; Pergamon Press Ltd.; Elsevier BV (ISSN 0097-8485)
- Published
- 1999
- Language
- EN
- Field
- Chemistry (Physical Sciences)