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Ab0176 Pathological Phenotypes Of Body Composition In Patients With Rheumatoid Arthritis by A. Feklistov; N. Toroptsova; O. Nikitinskaya; A. Efremova; N. Demin is a Medicine article available to read on EtoBox.

What is Ab0176 Pathological Phenotypes Of Body Composition In Patients With Rheumatoid Arthritis about?

## Background: Inflammation, decreased physical activity, hormonal disorders, and the use of glucocorticoids lead to changes in the composition of the body in rheumatoid arthritis (RA). Various combinations of decreased muscle and bone mass and increased adipose tissue have led to the release of various pathological phenotypes of the composition of the body. ## Objectives: To determine the frequency of pathological phenotypes of body composition in patients with RA. ## Methods: The study included 79 women with RA, with a median age of 60 y.o. [55; 65]. 92% of the women were postmenopausal. The median duration of the disease was 9 years [3; 11]. Basic anti-inflammatory therapy was received by 81% of patients. Methotrexate was used most often as the basic therapy – in 52% of cases. 49% of patients were treated with glucocorticoid drugs. All patients underwent dual-energy X-ray absorptiometry. The mineral density of the tissues was determined in the standard measurement areas - the spine and the proximal thigh, and the content of muscle and adipose tissue was analyzed. We calculated appendicular muscle mass (AMM), which is the sum of upper and lower limb muscle mass and appendicular m

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Author

A. Feklistov; N. Toroptsova; O. Nikitinskaya; A. Efremova; N. Demin

Publisher

BMJ

Published

2021

Language

EN

Field

Medicine (Health Sciences)