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Interactions of HIV-1 with antigen-presenting cells by Hewson, Tim; Lone, Nazir; Moore, Marilyn; Howie, Sarah is a Immunology and Microbiology article available to read on EtoBox.

What is Interactions of HIV-1 with antigen-presenting cells about?

There is currently much interest in the numerical and functional loss of antigen‐presenting cells (APC) in HIV‐1 disease and the contribution that this may make to HIV‐1 pathology. The HIV‐1 virus can interfere with the normal function of APC in a number of ways involving inappropriate signalling. These include changes in cytokine balance, cell‐surface molecule expression and intracellular signalling pathways. This review examines how HIV‐1 is able to disregulate APC function and discusses possible outcomes for the function of the immune system.

Who reads Interactions of HIV-1 with antigen-presenting cells?

Author

Hewson, Tim; Lone, Nazir; Moore, Marilyn; Howie, Sarah

Publisher

Nature Publishing Group; Wiley (Blackwell Publishing); John Wiley and Sons Inc.; Wiley (ISSN 0818-9641)

Published

1999

Language

EN

Field

Immunology and Microbiology (Life Sciences)