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The 1st International Electronic Conference on Pharmaceutics by Németh, Zsófia (author);Pallagi, Edina (author);Dobó, Dorina Gabriella (author);Csóka, Ildikó (author) is a nonfiction available to read on EtoBox.
What is The 1st International Electronic Conference on Pharmaceutics about?
Trans-resveratrol, due to its antioxidant property, has the potential to be successfully applied in the prevention and the treatment of neurological disorders (Parkinson's and Alzheimer's disease). Nevertheless, its traditional administration (intravenous, oral) and bioavailability are limited by its physical-chemical characteristics (solubility, chemical instability, sensitivity to heat, UVlight and pH). The 'nose-to-brain' application, as an alternate administration route, represents a way to reach the brain without the limitations of the blood-brain barrier, while the use of nano-sized drug delivery systems, like the liposomes, can overcome the developmental and therapeutic issues of the formulations. This research paper shows the application of Risk Assessment (RA), the key element of the Quality by Design mindset, in the development of a liposomal resveratrol-containing formulation with brain target and nasal administration. The study intends to demonstrate the definition of the quality target product profile, the selection of the critical factors, and the application of the RA to get a detailed view on the critical parts of the development process. On these terms, the factors
Who reads The 1st International Electronic Conference on Pharmaceutics?
It is typically read by self-directed learners exploring a subject in depth.
Common subject areas: history, science, philosophy, social sciences.
- Author
- Németh, Zsófia (author);Pallagi, Edina (author);Dobó, Dorina Gabriella (author);Csóka, Ildikó (author)
- Publisher
- MDPI
- Published
- 2020
- Language
- EN
- Category
- nonfiction
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