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A prosthetic myocardium for repair of localized defects of the left ventricle: Concept and hemodynamic feasibility by A. Kantrowitz; T. Igari; I. Hayashi; P.S. Freed is a Medicine article available to read on EtoBox.

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As an approach to the treatment of patients with large but circumscribed akinetic or dyskinetic regions in the left ventricular myocardium as sequelae of acute myocardial infarction, excision of the defect and implantation of a mechanical functional equivalent of myocardium is suggested. Experimental investigation of this technique is described. Hemodynamic data from a series of dog experiments indicate that activation of the prosthetic myocardium after excision of the left ventricle is followed by improvement in various hemodynamic parametres of interest Although substantial experimental work must be completed and difficult bioengineering problems solved, preliminary results have encouraged us to continue our investigations of the prosthetic myocardium. An imposing array of treatment methods is now available to the clinician who must deal with the sequelae of acute myocardial infarction. Selecting from pharmacologic, electrophysiologic, and surgical approaches the physician can in many instances design a treatment plan precisely tailored to the clinical problem. Large left ventricular aneurysms and their functional equivalents of ventricular dyskinesis or hypokinesis continue, how

Who reads A prosthetic myocardium for repair of localized defects of the left ventricle: Concept and hemodynamic feasibility?

Author

A. Kantrowitz; T. Igari; I. Hayashi; P.S. Freed

Publisher

SAGE Publications

Published

1980

Language

EN

Field

Medicine (Health Sciences)