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Can I read Network Inefficiencies in Autism Spectrum Disorder at 24 Months on EtoBox?
Network Inefficiencies in Autism Spectrum Disorder at 24 Months by J D Lewis; A C Evans; J R Pruett; K Botteron; L Zwaigenbaum; A Estes; G Gerig; L Collins; P Kostopoulos; R McKinstry; S Dager; S Paterson; R T Schultz; M Styner; H Hazlett; J Piven; for the IBIS network is a Neuroscience article available to read on EtoBox.
What is Network Inefficiencies in Autism Spectrum Disorder at 24 Months about?
Autism spectrum disorder (ASD) is a developmental disorder defined by behavioral symptoms that emerge during the first years of life. Associated with these symptoms are differences in the structure of a wide array of brain regions, and in the connectivity between these regions. However, the use of cohorts with large age variability and participants past the generally recognized age of onset of the defining behaviors means that many of the reported abnormalities may be a result of cascade effects of developmentally earlier deviations. This study assessed differences in connectivity in ASD at the age at which the defining behaviors first become clear. There were 113 24-month-old participants at high risk for ASD, 31 of whom were classified as ASD, and 23 typically developing 24-month-old participants at low risk for ASD. Utilizing diffusion data to obtain measures of the length and strength of connections between anatomical regions, we performed an analysis of network efficiency. Our results showed significantly decreased local and global efficiency over temporal, parietal and occipital lobes in high-risk infants classified as ASD, relative to both low- and high-risk infants not clas
Who reads Network Inefficiencies in Autism Spectrum Disorder at 24 Months?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- J D Lewis; A C Evans; J R Pruett; K Botteron; L Zwaigenbaum; A Estes; G Gerig; L Collins; P Kostopoulos; R McKinstry; S Dager; S Paterson; R T Schultz; M Styner; H Hazlett; J Piven; for the IBIS network
- Publisher
- Nature Publishing Group; Springer Science and Business Media LLC (ISSN 2158-3188)
- Published
- 2014
- Language
- EN
- Field
- Neuroscience (Life Sciences)