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What is Methotrexate in Oral Surgery Guide about?

Methotrexate (MTX) is an antimetabolite used in low doses for autoimmune diseases and in high doses for cancer treatment, primarily acting by inhibiting dihydrofolate reductase. In oral and maxillofacial surgery, it is indicated for conditions like oral lichen planus and TMJ inflammatory arthritis, but can cause side effects such as oral mucositis and delayed wound healing. Surgical considerations include continuing MTX for minor procedures while major surgeries may require temporary discontinuation, and co

Author

Bader Fatani

Language

EN