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Impact of Right Ventricular Stiffness on Discordance Between Hemodynamic Parameter and Regurgitant Volume in Patients with Pulmonary Regurgitation by Ko Motoi; Hiroyuki Iwano; Satonori Tsuneta; Suguru Ishizaka; Yoji Tamaki; Hiroyuki Aoyagi; Kosuke Nakamura; Michito Murayama; Masahiro Nakabachi; Shinobu Yokoyama; Hisao Nishino; Sanae Kaga; Atsuhito Takeda; Toshihisa Anzai is a Medicine article available to read on EtoBox.
What is Impact of Right Ventricular Stiffness on Discordance Between Hemodynamic Parameter and Regurgitant Volume in Patients with Pulmonary Regurgitation about?
Background: Accurate detection of significant pulmonary regurgitation (PR) is critical in management of patients after right ventricular (RV) outflow reconstruction in Tetralogy of Fallot (TOF) patients, because of its influence on adverse outcomes. Although pressure half time (PHT) of PR velocity is one of the widely used echocardiographic markers of the severity, shortened PHT is suggested to be seen in conditions with increased RV stiffness with mild PR. However, little has been reported about the exact characteristics of patients showing discrepancy between PHT and PR volume in this population. Methods: Echocardiography and cardiac magnetic resonance imaging (MRI) were performed in 74 TOF patients after right ventricular outflow tract (RVOT) reconstruction [32 ± 10 years old]. PHT was measured from the continuous Doppler PR flow velocity profile and PHT < 100 ms was used as a sign of significant PR. Presence of end-diastolic RVOT forward flow was defined as RV restrictive physiology. By using phase-contrast MRI, forward and regurgitant volumes through the RVOT were measured and regurgitation fraction was calculated. Significant PR was defined as regurgitant fraction ≥ 25%. Resu
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- Author
- Ko Motoi; Hiroyuki Iwano; Satonori Tsuneta; Suguru Ishizaka; Yoji Tamaki; Hiroyuki Aoyagi; Kosuke Nakamura; Michito Murayama; Masahiro Nakabachi; Shinobu Yokoyama; Hisao Nishino; Sanae Kaga; Atsuhito Takeda; Toshihisa Anzai
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)