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Methylene Blue Dye Versus Combined Dye-radioactive Tracer Technique for Sentinel Lymph Node Localisation in Early Breast Cancer by P. Varghese; A. Mostafa; A.T. Abdel-Rahman; S. Akberali; J. Gattuso; A. Canizales; C.A. Wells; R. Carpenter is a Medicine article available to read on EtoBox.

What is Methylene Blue Dye Versus Combined Dye-radioactive Tracer Technique for Sentinel Lymph Node Localisation in Early Breast Cancer about?

## Aim: The study compared the accuracy and success rate of two techniques, methylene blue alone versus combined methylene blue and radioactive colloid in sentinel lymph node localisation in the management early breast cancer. ## Methods: Three hundred and twenty-nine patients with tumours less than 2 cm on ultrasound assessment were prospectively evaluated. one hundred and seventy-three patients (group a) underwent sentinel lymph node localisation using 1 ml of 1% methylene blue. a combined technique of both methylene blue and radioactive colloid was used in 156 patients (group b). application of both was subdermal and subareolar. sentinel lymph nodes were examined by standard microscopy. patients underwent breast conservation surgery or mastectomy and sentinel node guided four node axillary sampling+/-clearance. ## Results: In group a, the sentinel lymph node identification rate was 96.5%. the negative predictive value was 96.3%, with false negative of 3.7% and accuracy of 87.4%. in group b the identification rate for sentinel lymph node was 98.7%, with false negative of 4.1%, negative predictive value of 96%, and accuracy of 83.8%. ## Conclusion: Sentinel lymph node localisation

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Author

P. Varghese; A. Mostafa; A.T. Abdel-Rahman; S. Akberali; J. Gattuso; A. Canizales; C.A. Wells; R. Carpenter

Publisher

Elsevier Science; Elsevier ; W. B. Saunders Co., Ltd.; Elsevier BV (ISSN 0748-7983)

Published

2007

Language

EN

Field

Medicine (Health Sciences)