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Bbaf 187 by leopoldzehetner58 is a document available to read on EtoBox.
What is Bbaf 187 about?
The document presents DEKP, a deep learning model designed for predicting enzyme kinetic parameters (kcat and Km) using pretrained models and graph neural networks. DEKP effectively addresses limitations in prediction accuracy due to sequence similarity variations by integrating protein sequences, structures, and substrate data, outperforming existing models in accuracy. This model is expected to enhance enzyme screening processes and support enzyme-directed evolution research.
- Author
- leopoldzehetner58
- Language
- EN