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1) The study examined the effects of Rauwolfia alkaloids (RA) and reserpine on convulsions induced by camphor, leptazol, and strychnine in mice. 2) RA and reserpine were administered at 1/10 LD50, either alone or in combination with anti-epileptic drugs phenytoin, troxidone, and phenacemide. 3) The results showed that RA and reserpine had varying effects - they did not consistently prevent or potentiate convulsions, and they could both nullify and enhance the effects of anti-epileptic drugs, depending on
- Author
- Awanish Mishra
- Language
- EN