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Structural studies of the O-antigenic polysaccharides from Shigella dysenteriae type 3 and Escherichia coli O124, a reinvestigation by K. Hanna M. Jonsson; Andrej Weintraub; Göran Widmalm is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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The structures of the O-antigenic part of the lipopolysaccharides from Shigella dysenteriae type 3 and Escherichia coli O124 have been reinvestigated. (1)H and (13)C NMR spectroscopy in combination with selected 2D NMR techniques were used to determine the O-antigen pentasaccharide repeating units with the following structure: [see text]. From biosynthetic considerations this should also be the biological repeating unit. The structures of the repeating units also explain the previously observed cross-reactivity between the strains and to E. coli O164, which only differs in the terminal sugar residue that is lacking the (R)-1-carboxyethyl group.

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Author

K. Hanna M. Jonsson; Andrej Weintraub; Göran Widmalm

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0008-6215)

Published

2006

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)