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The Good, the Bad and the Ugly of Distribution Coefficients: Current Status, Views and Outlook by Franco Lombardo; Bernard Faller; Marina Shalaeva; Igor Tetko; Suzanne Tilton is a book available to read on EtoBox.
What is The Good, the Bad and the Ugly of Distribution Coefficients: Current Status, Views and Outlook about?
<p><p>this First Systematic Overview For More Than A Decade Is Tailor-made For The Medicinal Chemist. All The Chapters Are Written By Experienced Drug Developers And Include Practical Examples From Real Drug Candidates. <p>following An Introduction To Global Drug Properties And Their Impact On Drug Research, Screening And Combinatorial Chemistry Libraries, This Handbook Demonstrates The Best And Fastest Way To Estimate Those Properties Most Relevant For The Efficiency And Pharmacokinetic Performance Of A Drug Molecule: Lipophilicity, Solubility, Electronic Properties And Conformation. Finally, It Is Shown How Physico-chemical Drug Properties Guide Drug- And Lead-likeness.</p>
- Author
- Franco Lombardo; Bernard Faller; Marina Shalaeva; Igor Tetko; Suzanne Tilton
- Publisher
- Wiley-VCH; John Wiley & Sons
- Published
- 2007
- Language
- EN
- ISBN
- 9781282010598
- Subjects
- Medical, Science, Chemistry
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