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Congenital long QT syndrome and 2:1 atrioventricular block: An optimistic outcome in the current era by Peter F. Aziz; Ronn E. Tanel; Ilana J. Zelster; Robert H. Pass; Tammy S. Wieand; Victoria L. Vetter; R. Lee Vogel; Maully J. Shah is a Medicine article available to read on EtoBox.

What is Congenital long QT syndrome and 2:1 atrioventricular block: An optimistic outcome in the current era about?

## Background: Previous studies of patients with long qt syndrome (lqts) and 2:1 atrioventricular block (avb) have reported a mortality rate greater than 50% during infancy. ## Objective: The purpose of this study was to determine the outcome of this high-risk population in the current era. ## Methods: A retrospective study from four tertiary care pediatric centers assessed patients with congenital lqts and 2:1 avb from january 2000 to january 2009. all neonates who presented with 2:1 avb and prolonged qtc unrelated to medication were included in the study. statistical analysis was performed using a paired t-test. medical records were reviewed for ecg findings, genotype, medications, and device therapy. ## Results: Twelve patients that met the inclusion criteria were identified. all patients underwent diagnostic ecg in the first 24 hours of life. the average qtc interval prior to therapy was 616 +/- 99 ms (range 531-840 ms). over a follow-up period of 71 +/- 45 months (range 15-158 months), 11 of 12 patients received devices (8 permanent pacemaker, 3 implantable cardioverter-defibrillator). average age of device placement was 48 months (median 2 months, range 3 days to 10.5 years).

Who reads Congenital long QT syndrome and 2:1 atrioventricular block: An optimistic outcome in the current era?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Peter F. Aziz; Ronn E. Tanel; Ilana J. Zelster; Robert H. Pass; Tammy S. Wieand; Victoria L. Vetter; R. Lee Vogel; Maully J. Shah
Publisher
Elsevier BV
Published
2010
Language
EN
Field
Medicine (Health Sciences)

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